Allosteric binding sites

allosteric binding sites A type of binding site con­tained in many ENZYMEs and RECEPTORs. As a conse­quence of the binding to allosteric binding sites, the interaction with the normal ligand (ligands are molecules that bind to proteins) may be either enhanced or reduced. Ligand binding can change the shape of a protein.

allosteric effector Specific small molecules that bind to a protein at a site. Other than a catalytic site and that modulate (by activation or inhibition)the biological activity.