base-pair substitution

base-pair substitution There are two main types of mutations within a gene: base-pair substitutions and base-pair insertions or deletions. A base-pair substitu­tion is a point mutation; it is the replacement of one nucleotide and its partner from the complementary deoxyribonucleic acid (DNA) strand with another pair of nucleotides. Bases are one of five compounds—ade­nine, guanine, cytosine, thymine, and uracil—that form the genetic code in DNA and ribonucleic acid (RNA).

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